Appearance (Colour)
White or almost white, colourless
Appearance (Form)
Crystalline powder or crystals
Solubility
Very soluble in water,freely soluble in ethanol (96%)
Identification
A) By specific optical rotation
C) By TLC
Identification (IR Spectrum)
B) Passes
Appearance of Solution
2.5g in 50ml water is clear and colourless
Specific rotation [α]
-86.0° to -84.0° (dried substance) ( C=4, water)
Ninhydrin – Positive substance
Individual impurity : Max 0.2%
Total impurities: Max 0.5%
Chloride (CI)
Max. 200ppm
Sulphate (SO4)
Max. 300ppm
Ammonium (NH4)
NMT area of corresponding peak obtained from reference solution (c) (0.02%)
Iron (Fe)
Max. 10ppm
Loss on drying
Max. 0.5%
Sulphated Ash
Max. 0.1%
Assay (On dry basis)
98.5 – 101.0%
Reference
BP 2020
